Pubblicazione scientifica

Evaluation of the wound healing efficacy of chemical and phytogenic silver nanoparticles

FILONE TECNOLOGICO	TEMA
produzione e raccolta

RIASSUNTO

Wound healing requires a series of cellular events and a cascade of co-ordinated and systemic biochemical events. Silver nanoparticles possess many beneficial properties for wound management including antibacterial, anti-inflammatory and pro-healing properties. In this study, the authors investigated the wound healing properties of Cinnamomum verum extract mediated nanosilver (CENS) particles in comparison with 1% povidone iodine, citrate mediate NS and CE treatments. The topical application of CENS showed good antibacterial activity and accelerated wound healing with complete epithelialisation and normal re-growth of hair in all three models of study: namely, excision, incision and dead space models in rats compared with all other treatments. CENS was also found to promote collagen synthesis, stabilise wound besides countering oxidative stress and stimulating cellular proliferation CENS could be a novel therapeutic agent for wound management.

DATA

Data di pubblicazione: 27/09/2016

AUTORI

SREEVANI POTHIREDDY
ADILAXMAMMA KALIKI
ALPHA RAJ MEKAPOGU
MURALIDHAR YEGIREDDY
ESWARA PRASAD PAGADALA
TOLLAMADUGU NAGA VENKATA KRISHNA VARA PRASAD

ENTE DI AFFERENZA

DEPT VETERINARY PHARMACOLOGY & TOXICOLOGY COLL OF VETERINARY SCI TIRUPATI INDIA
DEPT VETERINARY PHARMACOLOGY & TOXICOLOGY COLL OF VETERINARY SCI PRODDATUR INDIA
DEPT VETERINARY BIOCHEM COLL OF VETERINARY SCI TIRUPATI INDIA
REGIONAL AGRIC RES STATION NANOTECHNOL CTR TIRUPATI INDIA

RIVISTA

IET Nanobiotechnology (Volume: 10, Issue: 5, Page(s): 340-348)

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