Pubblicazione scientifica

A Review of Fish Vaccine Development Strategies: Conventional Methods and Modern Biotechnological Approaches

FILONE TECNOLOGICO	TEMA
trasformazione e commercializzazione

RIASSUNTO

Fish immunization has been carried out for over 50 years and is generally accepted as an effective method for preventing a wide range of bacterial and viral diseases. Vaccination efforts contribute to environmental, social, and economic sustainability in global aquaculture. Most licensed fish vaccines have traditionally been inactivated microorganisms that were formulated with adjuvants and delivered through immersion or injection routes. Live vaccines are more efficacious, as they mimic natural pathogen infection and generate a strong antibody response, thus having a greater potential to be administered via oral or immersion routes. Modern vaccine technology has targeted specific pathogen components, and vaccines developed using such approaches may include subunit, or recombinant, DNA/RNA particle vaccines. These advanced technologies have been developed globally and appear to induce greater levels of immunity than traditional fish vaccines. Advanced technologies have shown great promise for the future of aquaculture vaccines and will provide health benefits and enhanced economic potential for producers. This review describes the use of conventional aquaculture vaccines and provides an overview of current molecular approaches and strategies that are promising for new aquaculture vaccine development.

DATA

Data di pubblicazione: 16/11/2019

AUTORI

MA JIE
BRUCE TIMOTHY J
JONES EVAN M
CAIN KENNETH D

ENTE DI AFFERENZA

DEPT FISH & WILDLIFE SCIENCES COLLEGE OF NATURAL RESOURCES UNIV IDAHO MOSCOW ID 83844 USA TBRUCE UIDAHO EDU TJB EVANJ UIDAHO EDU EMJ
AQUACULTURE RSCH INST UNIV IDAHO MOSCOW ID 83844 USA

RIVISTA

Microorganisms, 7(11), 569

IMPACT FACTOR

4,152

indietro