Pubblicazione scientifica

Waterborne aripiprazole blunts the stress response in zebrafish

FILONE TECNOLOGICO	TEMA
trasformazione e commercializzazione

RIASSUNTO

Here we provide, at least to our knowledge, the first evidence that aripiprazole (APPZ) in the water blunts the stress response of exposed fish in a concentration ten times lower than the concentration detected in the environment. Although the mechanism of APPZ in the neuroendocrine axis is not yet determined, our results highlight that the presence of APPZ residues in the environment may interfere with the stress responses in fish. Since an adequate stress response is crucial to restore fish homeostasis after stressors, fish with impaired stress response may have trouble to cope with natural and/or imposed stressors with consequences to their welfare and survival.

DATA

Data di pubblicazione: 22/11/2016

AUTORI

BARCELLOS HELOISA HELENA DE ALCANTARA
KALICHAK FABIANA
DA ROSA JOAO GABRIEL SANTOS
OLIVEIRA THIAGO ACOSTA
KOAKOSKI GESSI
IDALENCIO RENAN
DE ABREU MURILO SANDER
GIACOMINI ANA CRISTINA VARRONE
FAGUNDES MICHELE
VARIANI CRISTIANE
ROSSINI MAINARA
PIATO ANGELO L
BARCELLOS LEONARDO JOSE GIL

RIVISTA

Scientific Reports, 6, 37612

indietro