Pubblicazione scientifica

Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome

FILONE TECNOLOGICO	TEMA
trasformazione e commercializzazione

RIASSUNTO

Objective

To assess and compare salivary periodontopathic bacteria between groups of Down syndrome and non-Down syndrome children and adolescents.

Materials and Methods

This study included a sample of 30 Down syndrome children and adolescents (G-DS) and 30 age- and sex-matched non-Down syndrome subjects (G-ND). Clinical examination determined the gingival bleeding index (GBI) and plaque index. Unstimulated whole saliva samples were collected from all participants. The fluorescence in situ hybridization (FISH) technique identified the presence and density of eight periodontopathic bacteria in saliva. The statistical analysis included chi-square and Mann-Whitney U tests.

Results

In the G-DS group, bleeding on probing was more frequent (p = 0.037) and higher densities of Campylobacter rectus (p = 0.013), Porphyromonas gingivalis (p = 0.025), Treponema denticola (p = 0.026), Fusobacterium nucleatum (p = 0.013), Prevotella intermedia (p = 0.001) and Prevotella nigrescens (p = 0.008) were observed. Besides, in the G-DS, the densities of bacteria from the orange complex were significantly higher in the age group 3–7 years for F. nucleatum (p = 0.029), P. intermedia (p = 0.001) and P. nigrescens (p = 0.006). C. rectus was higher in the age group 8–12 years (p = 0.045).

Conclusion

The results showed that children and adolescents with Down syndrome have higher susceptibility to periodontal disease and number of periodontopathic bacteria.

DATA

Data di pubblicazione: 11/10/2016

AUTORI

FARIA CARRADA CAMILA
ALMEIDA RIBEIRO SCALIONI FLAVIA
EVANGELISTA CESAR DIONEIA
LOPES DEVITO KARINA
RIBEIRO LUIZ CLAUDIO
ALMEIDA RIBEIRO ROSANGELA

ENTE DI AFFERENZA

SCHOOL OF DENTISTRY FEDERAL UNIV JUIZ DE FORA JUIZ DE FORA MINAS GERAIS BRAZIL
DEPT PEDIATRIC DENTISTRY SCHOOL OF DENTISTRY FEDERAL UNIV JUIZ DE FORA JUIZ DE FORA MINAS GERAIS BRAZIL
DEPT ECOLOGY & MOLECULAR BIOLOGY OF MICROORGANISMS INST BIOLOGICAL SCIENCES FEDERAL UNIV JUIZ DE FORA JUIZ DE FORA MINAS GERAIS BRAZIL
DEPT DENTAL CLINIC SCHOOL OF DENTISTRY FEDERAL UNIV JUIZ DE FORA JUIZ DE FORA MINAS GERAIS BRAZIL
DEPT STATISTICS INST EXACT SCIENCES FEDERAL UNIV JUIZ DE FORA JUIZ DE FORA MINAS GERAIS BRAZIL
UNIV PACIFIC US

RIVISTA

PLoS ONE, 11(10), e0162988

IMPACT FACTOR

2,870

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