Pubblicazione scientifica

Fish oil supplements, longevity and aging

FILONE TECNOLOGICO	TEMA
trasformazione e commercializzazione

RIASSUNTO

Fish oil supplementation is of great medical and public interest with epidemiological evidence of health benefits in humans, in particular by conferring protection against heart diseases. Its anti-inflammatory properties have also been reported. Initial results from short-lived mouse strains showed that fish oil can increase lifespan, affecting pathways like inflammation and oxidation thought to be involved in the regulation of aging. Could fish oil and its omega-3 fatty acids act as geroprotectors? Probably not. A new study by Strong et al. challenges the role for fish oil supplementation in aging. Using a large cohort of genetically heterogeneous mice in three sites, part of the Interventions Testing Program of the NIA, Strong et al. show that fish oil supplementation at either low or high dosages has no effect on the lifespan of male or female mice. Although it is still possible that fish oil supplementation has health benefits for specific age-related diseases, it does not appear to slow aging or have longevity benefits.

DATA

Data di pubblicazione: 25/08/2016

AUTORI

DE MAGALHAES JOAO PEDRO
MULLER MICHAEL
RAINGER G ED
STEEGENGA WILMA

ENTE DI AFFERENZA

INTEGRATIVE GENOMICS OF AGEING GROUP INST AGEING & CHRONIC DISEASE UNIV LIVERPOOL LIVERPOOL UK
NORWICH RSCH PARK FOOD & HEALTH ALLIANCE NORWICH UK
CTR CARDIOVASCULAR SCIENCES SCHOOL OF CLINICAL & EXPERIMENTAL MEDICINE MEDICAL SCHOOL UNIV BIRMINGHAM BIRMINGHAM UK
HUMAN NUTRITION WAGENINGEN UNIV & RSCH CTR WAGENINGEN NETHERLANDS

RIVISTA

Aging (Albany NY), 8(8), 1578-1582

IMPACT FACTOR

5,44

indietro