Pubblicazione scientifica

Anti-Biofilm Effect of Biodegradable Coatings Based on Hemibastadin Derivative in Marine Environment

FILONE TECNOLOGICO	TEMA
economia circolare e sostenibilità

RIASSUNTO

Dibromohemibastadin-1 (DBHB) is an already known potent inhibitor of blue mussel phenoloxidase (which is a key enzyme involved in bioadhesion). Within this study, the potentiality of DBHB against microfouling has been investigated. The activity of DBHB was evaluated on key strains of bacteria and microalgae involved in marine biofilm formation and bioassays assessing impact on growth, adhesion and biofilm formation were used. To assess the efficiency of DBHB when included in a matrix, DBHB varnish was prepared and the anti-microfouling activity of coatings was assessed. Both in vitro and in situ immersions were carried out. Confocal Laser Scanning Microscopy (CLSM) was principally used to determine the biovolume and average thickness of biofilms developed on the coatings. Results showed an evident efficiency of DBHB as compound and varnish to reduce the biofilm development. The mode of action seems to be based principally on a perturbation of biofilm formation rather than on a biocidal activity in the tested conditions.

DATA

Data di pubblicazione: 13/07/2017

AUTORI

LE NORCY TIFFANY
NIEMANN HENDRIK
PROKSCH PETER
LINOSSIER ISABELLE
VALLEE-REHEL KARINE
HELLIO CLAIRE
FAY FABIENNE

ENTE DI AFFERENZA

LAB DE BIOTECHNOLOGIE & CHIM MARINES INST UNIV EUR MER UNIV BRETAGNE SUD 56100 LORIENT FRANCE TIFFANY LE NORCY UNIV UBS FR TLN ISABELLE LINOSSIER UNIV UBS FR IL KARINE REHEL UNIV UBS FR KV R
INST PHARM BIOLOGY & BIOTECHNOLOGY HEINRICH HEINE UNIV DUSSELDORF 40225 DUSSELDORF GERMANY HENDRIK NIEMANN WEB DE HN PROKSCH UNI DUESSELDORF DE PP
BIODIMAR LEMAR UMR 6539 INST EUR MER UNIV BRETAGNE OCCIDENTALE 29200 BREST FRANCE CLAIRE HELLIO UNIV BREST FR

RIVISTA

International Journal of Molecular Sciences, 18(7), 1520

IMPACT FACTOR

4,210

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