Pubblicazione scientifica

Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions

FILONE TECNOLOGICO	TEMA
produzione e raccolta

RIASSUNTO

In this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose and sodium chloride. Using a dedicated algorithm, the measured data was analyzed and a high correlation coefficient R2 = 0.8647 was achieved. The experiment showed that the described technique allowed for the detection of various CsA concentration levels in a selective, label-free and simple way. This method could be used in medicine, veterinary medicine and laboratory diagnostics.

DATA

Data di pubblicazione: 22/06/2018

AUTORI

MARZEJON MARCIN
KOSOWSKA MONIKA
MAJCHROWICZ DARIA
BUŁŁO-PIONTECKA BARBARA
WASOWICZ MICHAŁ
JEDRZEJEWSKA-SZCZERSKA MAŁGORZATA

ENTE DI AFFERENZA

Department of Metrology and Optoelectronics Faculty of Electronics Telecommunications and Informatics Gdańsk University of Technology 11/12 Narutowicza Street 80-233 Gdansk Poland; marcin.marzejon.pg@gmail.com (M.M.); nika.kosowska@gmail.com (M.K.)
Department of Nephrology Transplantology and Internal Diseases Faculty of Medicine Medical University of Gdańsk 3a Marii Skłodowskiej-Curie Street 80-210 Gdansk Poland; bbullo@gumed.edu.pl
DEPT MORPHOLOGICAL SCIENCES FACULTY OF VETERINARY MEDICINE WARSAW UNIV LIFE SCIENCES

RIVISTA

Sensors (Basel, Switzerland), 18(7), 2001

IMPACT FACTOR

3,510

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