Pubblicazione scientifica

Teleosts Genomics: Progress and Prospects in Disease Prevention and Control

FILONE TECNOLOGICO	TEMA
economia circolare e sostenibilità
produzione e raccolta
trasformazione e commercializzazione

RIASSUNTO

Genome wide studies based on conventional molecular tools and upcoming omics technologies are beginning to gain functional applications in the control and prevention of diseases in teleosts fish. Herein, we provide insights into current progress and prospects in the use genomics studies for the control and prevention of fish diseases. Metagenomics has emerged to be an important tool used to identify emerging infectious diseases for the timely design of rational disease control strategies, determining microbial compositions in different aquatic environments used for fish farming and the use of host microbiota to monitor the health status of fish. Expounding the use of antimicrobial peptides (AMPs) as therapeutic agents against different pathogens as well as elucidating their role in tissue regeneration is another vital aspect of genomics studies that had taken precedent in recent years. In vaccine development, prospects made include the identification of highly immunogenic proteins for use in recombinant vaccine designs as well as identifying gene signatures that correlate with protective immunity for use as benchmarks in optimizing vaccine efficacy. Progress in quantitative trait loci (QTL) mapping is beginning to yield considerable success in identifying resistant traits against some of the highly infectious diseases that have previously ravaged the aquaculture industry. Altogether, the synopsis put forth shows that genomics studies are beginning to yield positive contribution in the prevention and control of fish diseases in aquaculture.

DATA

Data di pubblicazione: 04/04/2018

AUTORI

MWEEMBA MUNANG’ANDU HETRON
GALINDO-VILLEGAS JORGE
DAVID LIOR

ENTE DI AFFERENZA

NORWEGIAN UNIV LIFE SCIENCES FACULTY OF VETERINARY MEDICINE & BIOSCIENCES DEPT BASIC SCIENCES & AQUATIC MEDICINE SECTION OF AQUATIC MEDICINE & NUTRITION ADAMSTUEN CAMPUS ULLEVALSVEIEN
DEPT CELL BIOLOGY & HISTOLOGY FACULTY OF BIOLOGY INST BIOMEDICAL RSCH OF MURCIA ARRIXACA CAMPUS UNIVERSITARIO DE ESPINARDO UNIV MURCIA 30100 MURCIA SPAIN JORGE GALINDO UM ES
DEPT ANIMAL SCIENCES RH SMITH FACULTY OF AGRICULTURE FOOD & ENVIRONMENT HEBREW UNIV JERUSALEM

RIVISTA

International Journal of Molecular Sciences, 19(4), 1083

IMPACT FACTOR

4,210

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