Acquacoltura Pubblicazione scientifica Effect of levamisole, Vitamin E, and selenium against aflatoxicosis in broilers chicken FILONE TECNOLOGICO TEMA produzione e raccolta RIASSUNTO Aim:The experiment was conducted to determine of levamisole (0.2 ml/kg-BW), Vitamin E (80 mg)+selenium (1.6 mg), and aflatoxin (B1) (positive control) compared with group without aflatoxin (negative control) on some liver enzymes (aspartate transaminase [AST] and alanine transaminase [ALT]), as well as to study the histopathological changes.Materials and Methods:The experiment included (200) 1-day-old broilers Ross 308 (Turkey source) mixed sexes. They were divided into four equal groups (50 chicks each group). The experimental period was extended to 35 days.Results:The results revealed that the levels of liver enzymes (ALT and AST) of all groups at 35 days were significantly (p<0.05) higher than the negative control. Furthermore, the result of histopathological changes in thymus and Harderian gland in different ages of group Vitamin E+selenium showed a reduction in the depletion of the cortex as well as lessening of congestion and hemorrhage and necrosis also decreasing in inflammatory cells in the thymus and Harderian gland.Conclusion:The study confirmed the protective effect of Vitamin E and levamisole by reducing harmful impacts of aflatoxin through their antioxidant effect as they improved the liver enzymes and histopathological changes due to the toxin. DATA Data di pubblicazione: 01/02/2018 AUTORI ULAIWI AMJED H ENTE DI AFFERENZA DEPT PATHOLOGY & POULTRY DISEASES COLLEGE OF VETERINARY MEDICINE UNIV BAGHDAD IRAQ RIVISTA Veterinary World, 11(2), 248-253 IMPACT FACTOR 1,22