Pubblicazione scientifica

Modulation of lipid biosynthesis by stress in diatoms

FILONE TECNOLOGICO	TEMA
produzione e raccolta

RIASSUNTO

Diatoms are responsible for up to 40% of the carbon fixation in our oceans. The fixed carbon is moved through carbon metabolism towards the synthesis of organic molecules that are consumed through interlocking foodwebs, and this process is strongly impacted by the abiotic environment. However, it has become evident that diatoms can be used as ‘platform’ organisms for the production of high valuable bio-products such as lipids, pigments and carbohydrates where stress conditions can be used to direct carbon metabolism towards the commercial production of these compounds. In the first section of this review, some aspects of carbon metabolism in diatoms and how it is impacted by environmental factors are briefly described. The second section is focused on the biosynthesis of lipids and in particular omega-3 long-chain polyunsaturated fatty acids and how low temperature stress impacts on the production of these compounds. In a third section, we review the recent advances in bioengineering for lipid production. Finally, we discuss new perspectives for designing strains for the sustainable production of high-value lipids.

This article is part of the themed issue ‘The peculiar carbon metabolism in diatoms’.

DATA

Data di pubblicazione: 17/07/2017

AUTORI

SAYANOVA OLGA
MIMOUNI VIRGINIE
ULMANN LIONEL
MORANT-MANCEAU ANNICK
PASQUET VIRGINIE
SCHOEFS BENOIT
NAPIER JOHNATHAN A

ENTE DI AFFERENZA

Metabolism Bioengineering of Microalgal Molecules and Applications Mer Molécules Santé UBL IUML—FR 3473 CNRS University of Le Mans Le Mans-Laval France
DEPT PLANT SCIENCES ROTHAMSTED RSCH HARPENDEN AL5 2JQ UK

RIVISTA

Philosophical Transactions of the Royal Society B: Biological Sciences, 372(1728), 20160407

IMPACT FACTOR

6,090

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